EXTRACTION AND FRACTIONATION OF DATURA METEL LINN PHYTOCONSTITUENTS AND THEIR EVALUATION AS ANTIBACTERIAL COMPOUNDS
Authors: Tabani U , JANI A, PUROHIT R, PATEL B, SORATHIYA R, JANGBARI N AND RANA A

ABSTRACT
The pharmacological properties of Datura metel Linn are well known. The current study aimed to investigate the antibacterial activity of methanol extract and fractions of D. metel L. leaves. The presence of alkaloids, flavonoids, saponins, and steroids is revealed by a primarily qualitative analysis of phytochemicals. Using the agar well diffusion method, MIC, and MBC, antibacterial activity against human pathogens such as E. coli, S. enterica typhimurium, S. flexneri, and S. aureus revealed the presence of phytochemicals responsible for the killing of pathogens. Methanol extract fractions also had significant antibacterial activity. Keywords: Datura metel Linn, Phytoconstituents, Antibacterial agent, Fractionation
Publication date: 01/04/2023
    https://ijbpas.com/pdf/2023/April/MS_IJBPAS_2023_7067.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.4.7067