EXTRACTION AND FRACTIONATION OF DATURA METEL LINN PHYTOCONSTITUENTS AND THEIR EVALUATION AS ANTIBACTERIAL COMPOUNDS Authors: Tabani U , JANI A, PUROHIT R, PATEL B, SORATHIYA R, JANGBARI N AND RANA A
ABSTRACT
The pharmacological properties of Datura metel Linn are well known. The current study aimed to
investigate the antibacterial activity of methanol extract and fractions of D. metel L. leaves. The
presence of alkaloids, flavonoids, saponins, and steroids is revealed by a primarily qualitative analysis
of phytochemicals. Using the agar well diffusion method, MIC, and MBC, antibacterial activity
against human pathogens such as E. coli, S. enterica typhimurium, S. flexneri, and S. aureus revealed
the presence of phytochemicals responsible for the killing of pathogens. Methanol extract fractions
also had significant antibacterial activity.
Keywords: Datura metel Linn, Phytoconstituents, Antibacterial agent, Fractionation Publication date: 01/04/2023 https://ijbpas.com/pdf/2023/April/MS_IJBPAS_2023_7067.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.4.7067