A COMPREHENSIVE REVIEW: ORAL THIN FILMS AS MULTI- FACETED DRUG DELIVERY SYSTEM Authors: Bhattacharjee S , SARKAR D, BHATTACHARJEE R, BHATTACHARJEE S, AND DEBNATH B
ABSTRACT
The most popular route of administration is oral route because of low cost and better patient
compliance. Tablets and capsules are the most popular dosage forms taken through oral route,
but many paediatric & geriatric patients find it difficult to swallow and do not take their
medicines as prescribed. To overcome these difficulties, several fast-dissolving oral thin film
drug delivery systems are developed. This is convenient and straight forward to use compared
to other delivery types like orally disintegrating tablets. When thin film is kept on tongue, it
disintegrates and dissolves in very less time without intake of water so it is easy to swallow
and most convenient for patients. This review will give the overview of advantages &
disadvantages of oral thin film technology, ideal characteristics of drug to be selected,
manufacturing processes, novel technologies, polymers used & evaluation of oral thin films.
Keywords: Oral disintegrating film, oral strip, paediatric and geriatric patients, Novel drug
delivery system, Polymers, Plasticizers, Preparation techniques; Methods; Technologies
Publication date: 01/04/2023 https://ijbpas.com/pdf/2023/April/MS_IJBPAS_2023_7052.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.4.7052