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DETECTION OF ENTEROVIRUSES AND ADENOVIRUS BY REAL- TIME POLYMERASE CHAIN REACTION IN CELL CULTURE NEGATIVE STOOL SPECIMENS OF PATIENTS WITH ACUTE FLACCID PARALYSIS IN MOROCCO
Authors: Lemrabet S , ZAHER H, RAISS N, ANNAN A, IDRISSI AZZOUZI LM, FILALI MALTOUF A, MEDRAOUI L AND OUMZIL H

ABSTRACT
In the era of polio eradication, acute flaccid paralysis (AFP), a major clinical presentation of poliovirus infection, continues to pose a public health problem. Several infectious agents comprising different families of viruses have been isolated from cases of AFP. Non-polio Enteroviruses (NPEVs) are considered to be the main infectious agents in AFP cases; further investigations have shown the isolation of Adenovirus from the stools of these patients. However, some Enteroviruses do not grow in the conventional cell lines used for the detection of Enteroviruses which is laborious and time consuming. Thus, more sensitive and faster methods are urgently needed for accurate detection of Enteroviruses in stool samples from AFP cases.
Publication date: 01/04/2023
    https://ijbpas.com/pdf/2023/April/MS_IJBPAS_2023_7036.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.4.7036

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