ABSTRACT

The herbal plants are composed of a lot of active phytochemicals against pathogens, free radicals and hyperglycemia which provide an alternative means of therapy for various illnesses. The present study is designed to evaluate the biological properties of a polyphenol-rich fraction of the stem of Coscinium fenestratum and the leaves of Mukia maderaspatana. The antiradical activity of extracts was evaluated and the inhibition percentage of the ABTS radical activity was assessed on average and high free radical-scavenging values were found in a polyphenol-rich fraction of Coscinium fenestratum 74.16% and Mukia maderaspatana 71.29%. The antioxidant activity of extracts showed a strong positive correlation with the total phenolic content of the extract. The antibacterial effect of extracts showed more inhibitory activities against Escherichia coli, Pseudomonas aeruginosa and moderate action on Staphylococcus aureus, Enterococcus faecalis. The crude extracts had a lower level of sugars induced by amylase, glucosidase, and glucose absorption activities have inhibitory effects (EC50). As a consequence, their biochemical inhibitory impact might have been due to a synergistic impact among the phenolic chemicals present in the extract. Keywords: Phytochemical, Polyphenol, Hyperglycemia, Antioxidant, Antibacterial
Publication date: 01/03/2023

https://ijbpas.com/pdf/2023/March/MS_IJBPAS_2023_6940.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.3.6940