ABSTRACT

The spread of drug resistant bacteria has badly affected the efficiency of many known antibacterial agents. Thus, the need of new antibacterial drugs is increased. Plant based drugs are gaining more importance because herbal drugs are considered safe and dependable. Comparison between antibacterial activity of synthetic and natural carbazole derivatives were carried out. Microwave assisted synthesis of synthetic carbazole derivatives and Soxhlet extraction of carbazole alkaloid from Murraya koenigii were carried out. Binding scores obtained from molecular docking studies, zone of inhibition from the experimental antibacterial study are used as the parameters for comparison. Keywords: Docking, N-mannich base of carbazole, carbazole alkaloid, Murraya koenigii, Zone of inhibition, Binding energy
Publication date: 01/03/2023

https://ijbpas.com/pdf/2023/March/MS_IJBPAS_2023_6925.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2023/12.3.6925