NANOSTRUCTURED LIPID CARRIERS (NLC) FOR TOPICAL DELIVERY OF ANTIFUNGAL DRUGS: RECENT ADVANCEMENT FABRICATION AND CHARACTERIZATION METHOD Authors: Kumar M , SINGH N, KUMAR S, SHARMA N, KUMAR A, PAUL P, SINGH L, PANDEY RK AND ARORA K
ABSTRACT
Fungal infections are common amongst global populations. The major problem is drug targeted
delivery because the therapeutic dose does not reach the targeted sites. Nanotechnologies have
proven their efficacy in many diseases. In this review work, we have highlighted the gross
structure of the skin and various methods for the preparation of nanostructured lipid carrier’s
which can play in the development of future research related to fungal infections. Nanocarrier
systems are the potential for immediate drug release triggered by typical formulations, thus reducing the risk of some allergic/toxic reactions. Furthermore, the need of the hour is to design
to improve the penetration power of antifungal drugs, resulting in more effective and well-
organized treatment in fungal skin infections. When more commercial preparations become
usable, these carrier systems can prove their effectiveness over traditional drug delivery systems.
Keywords: Fungal infection, lipid nanoparticles, nanostructured lipid carriers, and topical route Publication date: 01/02/2023 https://ijbpas.com/pdf/2023/February/MS_IJBPAS_2023_6884.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.2.6884