A RETROSPECTIVE CASE SERIES ON SLE {SYSTEMATIC LUPUS ERTHYMATOSUS} IN 2 SIBLINGS OF SAME FAMILY
Authors: M. Meghana Goud , V MOHAN GOUD AND M. KRANTHI KUMAR

ABSTRACT
Patient: female patient at age 23 Department / ward: rheumatology Chief complaints: fever since 8 months, polyarthritis since 8 months, anemia Final diagnosis: systematic lupus erythematosus with nephritis Background: Systemic lupus erythematosus is characterized by multiorgan involvement and the presence of autoantibodies (SLE). Because of the vast spectrum of symptoms and signs, SLE's development and organ involvement are unpredictable. SLE is characterized by cytopenia’s such as anemia, leukopenia, and thrombocytopenia. Here the patient has lupus with nephritis and also thrombocytopenia. CASE 1: We report a case of a young Indian female who presented with severe anaemia, fever since 8 months and polyarthritis since 8 months and also leukopenia, subsequently diagnosed as TB and several many other infections and then eventually SLE with nephritis. CASE 2: The other case concerns the above case's sibling, a 47-year-old woman who presented with a plantar psorium on the palms and feet since 5yrs, as well as an uncontrollable fever. These indications were initially misdiagnosed as psoriasis, dengue fever, and other, but it was eventually determined to be SLE with thrombocytopenia. Conclusion: SLE can cause nephritis, which is a complication. It's critical to understand this link because early detection and treatment are critical. Corticosteroids and immunosuppressants have been demonstrated to be effective in treating SLE and the nephritis that comes with it. Finally, the patients are still receiving treatment and are alive, even though with some or the other complications. Keywords: SLE, Thrombocytopenia, Nephritis, Discoid Rash, Fatty Liver, Covid 19
Publication date: 01/02/2023
    https://ijbpas.com/pdf/2023/February/MS_IJBPAS_2023_6811.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.2.6811