Cissus quadrangularis is a very well know medicinal plant which is indigenous to Asia and Africa.
Hadjod or bone setter; Cissus quadrangularis is a succulent herbal plant belonging to family Vitaceae. It
is a fleshy, cactus which is widely used as a common food item in India. The whole plant including all
parts such as stems, leaves, roots is documented to possess medicinal properties in ethnobotanical surveys
conducted by ethnobotanists in the traditional system of medicine. Cissus quadrangularis contains ;
Triterpenes i.e. - ?- and ?- amyrine, ?- sitosterol etc , Unsymmetric tetracyclic such as triterpenoids- d-
amyrin, 3,3',4,4'-tetra hydroxy biphenyl etc. and Flavonoids such as quercetin, kaempferol,
quadrangularins A,B,C etc. Stem extract has high percentage of calcium ions and phosphorus, both of
which is essential for bone growth. In Ayurveda this plant has been documented for the treatment of
osteoarthritis, rheumatoid arthritis, and osteoporosis. The plant’s stem juice is used to treat scurvy,
menstrual disorders, and epistaxis. Shoots decoction along with dry ginger and black pepper is given for
body pain. Cissus quadrangularis was found to be effective as antibacterial, antioxidant and free radical
scavenging potential, Central nervous system depressant, and antiulcer. Cissus quadrangularis also
effective as anthelmintic, analgesic, anti-inflammatory, anti-hemorrhoidal, anti-tumor, antipyretic, gastro
protective, melanin promotion, bone healing, anti-obesity etc . Thus Cissus quadrangularis is a magic
remedy in most of disease.
Keywords: Cissus quadrangularis, Flavonoids, Bone Healing, Osteoporosis
Publication date: 01/01/2023
https://ijbpas.com/pdf/2023/January/MS_IJBPAS_2023_6798.pdf
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https://doi.org/10.31032/IJBPAS/2023/12.1.6798