IMPACT OF TYPE 2 DIABETES MELLITUS AND HYPOTHYROIDISM ON CARDIOVASCULAR OUTCOMES FOLLOWING PERCUTANEOUS CORONARY INTERVENTION Authors: Gokila S , ANANDHI D, REVATHI K, SENTHIL KUMARAN S, SUBBAN V, MULLASARI AS, PHILIP DC AND ANANDAN H
ABSTRACT
The association between diabetes mellitus (DM) and hypothyroidism in cardiovascular
disease (CVD) is well established. Both are associated with significant adverse impacts on
patients undergoing percutaneous coronary interventions (PCI). DM is an independent
predictor of adverse outcomes after drug-eluting stent (DES) implantation. Despite
reasonable glycemic control in the peri-procedural period, DM is associated with worse
clinical outcomes than non-diabetic patients. Hypothyroidism leads to higher cardiovascular
comorbidities and is associated with an increased incidence of major adverse cardiac and
cerebrovascular events (MACCE) than euthyroidism in PCI patients. Low T3 syndrome has
also been associated with adverse outcomes in PCI patients. Diagnosis and optimal
management of hypothyroidism may improve outcomes in CAD patients undergoing PCI.
This review focus on the impact of T2DM and hypothyroidism in patients undergoing PCI.
Keywords: Acute coronary syndrome, Coronary artery disease, Endocrine disorder,
Revascularisation, Major adverse cardiac and cerebrovascular events Publication date: 01/01/2023 https://ijbpas.com/pdf/2023/January/MS_IJBPAS_2023_6778.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2023/12.1.6778