ABSTRACT

Rheumatoid arthritis (RA) is a disease of undetermined etiology and is defined as an inflammatory joint disease influencing almost 1% of the population worldwide. RA diagnosis is very difficult at early stages of disease as it is based on clinical symptoms. A serological marker that can be a disease specific autoantibody can prove useful in early diagnosis. The symptoms can be treated with the help of Non-steroidal anti-inflammatory drugs (NSAIDs), as drugs of 1st choice. The side effects associated with NSAIDs are limiting its use and switching to other alternative drugs such as corticosteroids, DMARDs and medicinal herbs. As per reports, 60-90% of the arthritis patients who are not satisfied with NSAIDs are switching towards complementary and alternative medicine (CAM). The alternative drugs were evaluated by using animal models of inflammation. The prevalence of RA in most methodologies near to 1% among adults, 2% 5% in men and women, respectively, by the 65 years of age in Caucasian populations. The frequency of RA grows with age and reaches its peak around the 4th and 6th decades. Keywords RA, NRAS, pathogenesis, etiology, inflammation
Publication date: 01/01/2023

https://ijbpas.com/pdf/2023/January/MS_IJBPAS_2023_6776.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.1.6776