ABSTRACT

A Niosomes is a non-ionic surfactant based liposomes, found to be mixture of cholesterol and non-ionic surfactants and are proved to be a promising drug carrier and has potential to reduce the side effects of drugs and increased therapeutic effectiveness in various diseases. Niosomes are multilamellar or unilamellar vesicles in which an aqueous solute solution is completely encapsulated by a membrane formed by surfactant macromolecules organised as a bilayer. Their structure is identical to that of a liposome, hence they can be used to represent alternate vesicular systems to liposomes. Niosomes addressed the issues related to drug insolubility, instability, low bioavailability, and rapid deterioration. This overview article represents the structure of niosomes, advantages, disadvantages, methods for niosomes preparations, characterization, and its application of the vesicular system. Keywords: Niosomes; Drug delivery; Applications; Types; Methods; Vesicular
Publication date: 01/01/2023

https://ijbpas.com/pdf/2023/January/MS_IJBPAS_2023_6748.pdf

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https://doi.org/10.31032/IJBPAS/2023/12.1.6748