ABSTRACT

Increased whole blood viscosity is associated with Mortality and morbidity of several diseases. There are various instruments that is used to measure blood Viscosity (shear rate 100/s). Pathogenesis and development of certain diseases like diabetes mellitus, cardiovascular diseases and haemorrhagic shock is mediated by endothelial cell dysfunction. Thus, it is important to regulate and monitor blood viscosity. Increased blood viscosity is partially owing to a greater fibrinogen content and partly due to a larger packed cell volume. Greater viscosity results in increased flow resistance. Increased blood viscosity may be one plausible biological mechanism through which increase in haematocrit and fibrinogen may promote ischaemic heart disease and stroke. Randomized control of viscosity reduction in the prevention of cardiovascular events by lowering high levels of haematocrit or plasma fibrinogen were discussed. Herbs which were used as an alternative therapy in blood thinning was discussed. The main purpose of this review is to examine the regulation of blood viscosity and its impact in illness prevention. Also, about the best therapy option (plasmapheresis) for changes in blood viscosity. Keywords: Alternative therapies, Blood viscosity, Hyperviscosity syndrome, phlebotomy, Plasmapheresis, Yield shear stress
Publication date: 01/12/2022

https://ijbpas.com/pdf/2022/December/MS_IJBPAS_2022_6625.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.12.6625