ABSTRACT

Natural products have a wide range of chemical ingredients. The plant Jasticia adhatoda was chosen from the Acanthaceae family for this investigation. Bronchodilator, expectorant, and antibacterial properties.Extraction of herb was done using suitable traditional methods and evaluated by various physicochemical methods for alkaloids, tannins, saponins, flavanoids, and phenolicsetc. Herbal extract was applied for the suitable dosage form development, particularly for pediatric patient followed by optimization studies. The primary alkaloid vasicine found in plant extract was identified and validated in the current investigation through early qualitative phytochemical screening. The color of the zone was compared to the shade of the reference standards for the quantitative measurement and confirmation of vasicine. Short-wave UV 254 nm dots were seen, as well as five spots in long-wave UV 366 nm.With a corresponding correlation coefficient, the linearity standard curve was determined between 2 and 6 g/spot. All tracks are shown in a 3D graph of uniformity at 254nm and 366nm. HPTLC examination revealed a vivid orange colored zone that corresponded to the presence of alkaloids discovered in this study. Keywords: Jasticia adhatoda, UV Spectroscopy, FTIR, RP-HPTLC
Publication date: 01/11/2022

https://ijbpas.com/pdf/2022/November/MS_IJBPAS_2022_6602.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.11.6602