ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF EXTRACTS OBTAINED FROM Oxalis corniculata linn Authors: Khamkar P. A , GAVITRE S. B., MALPURE P. S.*, KAPSE S. N., CHAVAN M. J. AND JADHAV K. R.
ABSTRACT
Oxalis corniculata linn is a plant that has traditionally been used to relieve pain and
inflammation. In mice, the hot plate method and acetic acid-induced writhing tests were used, whereas
in rats, the carrageenan-induced paw edema method was used. The entire plant was extracted in stages
using several solvents (petroleum ether, ethyl acetate, and methanol) in sequence of increasing
polarity. Alkaloids, steroids, flavonoids, terpenoids, glycosides, tannins, and phenolic substances were
discovered in the Oxalis corniculata linn. The analgesic and anti-inflammatory effects of both extracts
(100 mg/kg and 200 mg/kg) were significant (P0.01). The pharmacological activities discovered
provide a solid foundation for both classic claims and the exploration of novel and potential leads.
Keyword(S): Analgesic, anti-inflammatory activity, Petroleum ether extract, Ethyl acetate
extract, Methanolic extract Publication date: 01/11/2022 https://ijbpas.com/pdf/2022/November/MS_IJBPAS_2022_6583.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2022/11.11.6583