ABSTRACT

Microspheres are typically free flowing material having particle size ranging from 1-1000 µm comprise of drug and varieties of polymers in matrix or encapsulated form. Microspheres are multiparticulate carriers which are fabricated to achieve prolonged and controlled delivery of drugs with minimal side effects and improving patient compliance. Microspheres administrated by topical route, can avoid pre systemic metabolism, reduce side effects and improve the therapeutic activity of drug. This carrier delivery system offers numerous benefits over conventional dosage forms that lead to significant improvement in drug bioavailability. This review article mainly focuses on the basic concepts of microspheres along with their types, methods and materials of preparation along with latest advances of microspheres in topical delivery. Keywords: Tiny carriers, Microspheres, Topical drug delivery, Fungal diseases, bioavailability
Publication date: 01/11/2022

https://ijbpas.com/pdf/2022/November/MS_IJBPAS_2022_6562.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.11.6562