ABSTRACT

Incidence of Peptic Ulcer Disease is high among Indian population and showed the risk of intestinal cancer. Many medicinal plants possess antiulcer properties. Cleome gynandra whole plant is selected to assess its antiulcer activity on experimental modals. Ethanol induced ulcer assay was performed along with antioxidant assay. SOD, GPx, GSH, CAT and MDA were assessed using standard textual methods. CGWPAE and CGWPEE proved to be an excellent antiulcer and antioxidant agent, which is similar to omeprazole effect. These two extracts exhibited good ulcer protection effect and reduced gastric acid secretion and also gastric acidity. Experimental evidences confirmed that plant extracts regained its ulcer cure effect and antioxidant effect as like group I normal animals and confirmed power of this plant as an antioxidant and antiulcer agent, which could be due to its phytochemicals. Key words: Cleome gynandra, antiulcer study, antioxidant assay, whole plant
Publication date: 01/11/2022

https://ijbpas.com/pdf/2022/November/MS_IJBPAS_2022_6423.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.11.6423