MULTIVARIATE CALIBRATION TECHNIQUE AIDED UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF ALOGLIPTIN AND REMOGLIFLOZIN IN PHARMACEUTICAL DOSAGE FORM Authors: Deepika Reddy I , SEETHARAMAN R* , KOKILAMBIGAI KS, KAVITHA J AND LAKSHMI K S
ABSTRACT
The present work is to create a UV spectrophotometric method for estimating Alogliptin and
Remogliflozin etabonate in pharmaceutical tablets using a multivariate calibration technique.
The multivariate calibration method determines the absorbance at several wavelengths,
enabling more efficient measurement. The ultraviolet spectrophotometric approach was
developed and validated. All validation parameters adhere to ICH guidelines. The assay
findings obtained with the present method were comparable to those obtained with previously
published methods, and no statistical difference was seen. The proposed MVC technique can
be used to estimate Alogliptin and Remogliflozin etabonate on a routine basis.
Keywords Alogliptin, Remogliflozin etabonate, Multivariate Calibration, UV
Spectrophotometry, Wavelength Publication date: 01/10/2022 https://ijbpas.com/pdf/2022/October/MS_IJBPAS_2022_6502.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2022/11.10.6502