ABSTRACT

Rasasindura (Red sulphide of mercury), most commonly used in Kupipakwa Rasayana (medicine prepared in bottle) is a sublime product of a mixture of Shodhita Parada (purified mercury) and Shodhita Gandhaka (purified sulfur), and due to its wide therapeutic utility, it is used in several formulations. Analysis of the products becomes a mandatory to get the quality products. It becomes necessary to adopt modern analytical methodology to determine the important chemical constituents present in the drug qualitatively and quantitatively. Objectives: To assess the quality of Rasasindura. Methodology: The drugs were selected according to grahya lakshana’s and quantified by modern parameters. The Parada and Gandhaka shodhana, Preparation of Kajjali and Rasasindura were done according to the reference of Rasatarangini. Physicochemical and Analytical tests were done before and after preparation. Results: XRD report has shown major peaks of HgS, crystals are hexagonal and primitive in lattice. SEM shows particle size of 100nm. ICP-AES has shown concentration of Mercury and Sulphur as 9.822 and 11.336% respectively. Conclusion: XRD report has shown major peaks of HgS, crystals are hexagonal and primitive in lattice. SEM image has shown crystalline nature, Rasasindura of particle size 100nm – 1µm. ICP-AES has shown concentration of Mercury and Sulphur as 9.822 and 11.336% respectively. Quality of Rasasindura is as per standard guidelines Keywords- Rasasindura, NPST, XRD, ICP-AES, SEM
Publication date: 01/10/2022

https://ijbpas.com/pdf/2022/October/MS_IJBPAS_2022_6478.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.10.6478