ABSTRACT

The current work focuses on the creation and validation of a quick, sensitive, and accurate mulitivariate calibration approach utilizing UV spectrophotometric techniques for the assessment of Benedipine. The ?max of benedipine is at 237 nm. The multivariate calibration technique applies the linear regression equation by evaluating the link between concentration and absorbance at five distinct wavelength. The findings were processed statistically. The devised approach was verified as per the ICH criteria. The approach is accurate, precise, and linearity within the range of 7-13 µg mL-1. This statistical technique delivers optimal findings by reducing the variation arising from the instrumental or experimental circumstances. Keywords: Benedipine Hydrochloride, Multivariate Calibration, Hypertension, UV Spectrophotmetric
Publication date: 01/10/2022

https://ijbpas.com/pdf/2022/October/MS_IJBPAS_2022_6450.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.10.6450