Triazole is the most selected pharmacophore for research because of its various
pharmacological activities. This page seeks to highlight the work that has been done and
reported, as well as the chemistry and biological activity of 1,2,3-triazole and its derivatives,
which have been synthesized in recent years. A heterocyclic molecule with three nitrogen and
two carbon atoms is known as a triazole. Based on the difference in relative position, there
are two types of isomers each triazole has two tautomer's which differs only by NH bond.
Over the years, many studies have been done on the biological activity, synthesis and of
different triazole derivatives. Antimicrobial, anti-inflammatory, antimalarial, antiviral
antitubercular, anticancer, antidiabetic, antibacterial, antifungal, antiprotozoal, and receptorselective biological action are all demonstrated by triazole compounds. The research of
triazole derivatives biological evaluation has been a fascinating subject of pharmaceutical
chemistry. This review article focuses on triazole's pharmacological profile, with various
activities and examples presented in the form of figures.
Keywords: 1,2,3 Triazole, Anticancer, Antibacterial, Antifungal, Antiviral, Anti-diabetic
Publication date: 01/09/2022
https://ijbpas.com/pdf/2022/September/MS_IJBPAS_2022_6396.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.9.6396
