ABSTRACT

Atylosia barbata Baker. (family Fabaceae) is considered in system of folklore medicine in the treatment of diabetes, antioxidant, anti-inflammatory and anti-rheumatism. The present experimental investigation established the lipid lowering properties of ethanolic extract of leaves of Atylosia barbata Baker. on experimentally Dexamethasone induced rats. The lipid parameters studied are Total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), High density lipoprotein cholesterol (HDL-C), very low density lipoprotein cholesterol (VLD-C), Triglycerides and atherogenic index. Extract was administered orally for eight days at a dose of 600 and 1200 mg/kg in Dexamethasone induced rats. The level of TC, LDL-C, VLDL-C and triglycerides were reduced significantly. (p<0.001) while HDL-C level was significantly increased when compared to control groups of rats. In conclusion these suggested that ethanolic extract of leaves of Atylosia barbata Baker. can reduce the lipid levels significantly. Keywords: Atylosia barbata, Dexamethasone, leaves, Hyperlipidemia
Publication date: 01/09/2022

https://ijbpas.com/pdf/2022/September/MS_IJBPAS_2022_6390.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.9.6390