Carica papaya L. belongs to the family Caricaceae and is a well-known medicinal herb that
is used all over the world to cure diseases such as malaria, dengue fever, inflammation, skin
infections, etc. The present study is, therefore, aimed to investigate the phytochemical
constituents, GC-MS analysis, antioxidant potential, total phenolic & flavonoid contents in
the leaf extracts of C. papaya. Many secondary metabolites are present in both aaqueous and
methanolic extracts. TLC showed total 5 spots in the methanolic extract with different Rf
values. The presence of phenolics and flavonoids in plant extracts was also confirmed by
using UV-visible spectroscopy. The mean values of total phenolic and flavonoids contents
are 41.14 ± 3.99mg GAE/g &143.3 ± 29.57 mg QE/g respectively. The dose dependent total
antioxidant activity was observed. Further, retention time, peak area, and molecular weight
were used to perform GC-MS analysis and it revealed the presence of various bioactive
compounds. However, 9,12,15-Octadecatrienoic acid, methyl ester, (Z,Z,Z)- was found to
have the largest peak area (11.20%). The phytochemical, TLC and GC-MS profiling of
methanolic extraction revealed the presence of many bioactive compounds with important
medicinal properties. Hence, the presence of these phytochemicals could be responsible for
the therapeutic effects of the plant leaves.
Keywords: C. papaya, Ascorbic acid, Antioxidant Activity, Total Phenolic Content, Total
Flavonoids Contents
Publication date: 01/09/2022
https://ijbpas.com/pdf/2022/September/MS_IJBPAS_2022_6351.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.9.6351
