ABSTRACT

Background: Natural polymers in industrial applications such as medicine, agriculture, and other fields quickly increase. The increasing usage of natural biodegradable polymers in the pharmaceutical area has been seen. Aim: This paper aims to summarise the function of artificial and biological polymers in drug delivery systems for gastroprotective drugs. Methodology: a comprehensive description of all processes, interventions, and comparisons; artificial and natural polymers are being investigated. Results: Various natural polymers are utilised longer as drug transporters in drug distribution methods to increase bioavailability and therapeutic efficacy. Natural polymers in gastroprotective drug delivery systems have floating properties in the gastric system to increase gastric resident time and improve therapeutic efficacy. Especially for drugs with narrow therapeutic indexes like carvedilol, itopride, and glipizide. Conclusion: Natural polymers promote prolonged swelling, and the mucosal layer binding property makes natural polymers suited for gastroprotective drug delivery systems compared to synthetic polymers. Keywords: Gastroprotective drug delivery systems, Natural polymer, Synthetic polymer, Formulation, Drug transport
Publication date: 01/09/2022

https://ijbpas.com/pdf/2022/September/MS_IJBPAS_2022_6349.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2022/11.9.6349