IN-VITRO ANTI-UROLITHIATIC ACTIVITY OF EXTRACT OF CURCUMA LONGA L RHIZOMES ON DISSOLUTION OF KIDNEY STONES Authors: Islam M , ALAM F* , DEKA S, JUDDER MI, CHOUDHURY MRA, AMIN R, YAKIN J AND DEY BK
ABSTRACT
Background: Herbal formulations are known to be the most potent for their stone dissolving
properties. The products that are utilized for kidney stone dissolving activity inhibit the
calculogenesis by decreasing the size of stone forming agents such as calcium oxalate crystals,
uric acid crystals, calcium phosphate and cystine crystals.
Materials and Methods: Herbal stone dissolving formulations were prepared by using several
herbal extract. The Curcuma longa extract was prepared using ethanol by simple extraction
method. Experimental solution was prepared by dissolving the extract in distilled water in iodine
flask and stirred using magnetic stirrer for seven days.
Results: The solution of rhizomes of Curcuma longa showed potent kidney stone dissolving
property with that of the marketed formulation.
Conclusion: Dried rhizomes of Curcuma longa is contains a number of phytoconstituents like
alkaloids, glycosides, carbohydrates, tannins, diterpenes, saponins, etc. which can be considered
as a potent kidney stone dissolving agent.
Keywords: Curcuma longa, kidney stone, herbal extract, calcium oxalate crystals Publication date: 01/08/2022 https://ijbpas.com/pdf/2022/August/MS_IJBPAS_2022_6335.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2022/11.8.6335