IN-VITRO ANTI-UROLITHIATIC ACTIVITY OF EXTRACT OF CURCUMA LONGA L RHIZOMES ON DISSOLUTION OF KIDNEY STONES
Authors: Islam M , ALAM F* , DEKA S, JUDDER MI, CHOUDHURY MRA, AMIN R, YAKIN J AND DEY BK

ABSTRACT
Background: Herbal formulations are known to be the most potent for their stone dissolving properties. The products that are utilized for kidney stone dissolving activity inhibit the calculogenesis by decreasing the size of stone forming agents such as calcium oxalate crystals, uric acid crystals, calcium phosphate and cystine crystals. Materials and Methods: Herbal stone dissolving formulations were prepared by using several herbal extract. The Curcuma longa extract was prepared using ethanol by simple extraction method. Experimental solution was prepared by dissolving the extract in distilled water in iodine flask and stirred using magnetic stirrer for seven days. Results: The solution of rhizomes of Curcuma longa showed potent kidney stone dissolving property with that of the marketed formulation. Conclusion: Dried rhizomes of Curcuma longa is contains a number of phytoconstituents like alkaloids, glycosides, carbohydrates, tannins, diterpenes, saponins, etc. which can be considered as a potent kidney stone dissolving agent. Keywords: Curcuma longa, kidney stone, herbal extract, calcium oxalate crystals
Publication date: 01/08/2022
    https://ijbpas.com/pdf/2022/August/MS_IJBPAS_2022_6335.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.8.6335