ABSTRACT

Immunotherapy is revolutionizing in the treatment of cancer. In advanced stage patients it can achieve remarkable responses, including complete recovery and long-term survival. However, immunotherapy also has limitations, such as its relatively low response rate and the development of serious side effects. These deficiencies are gradually overcomed by improving our understanding of the immune system and establishing a combination of immunotherapy and other treatment modalities. Additionally, in recent years, advances in materials science, chemistry, nanotechnology have begun to affect immuno-oncology, resulting in more efficacious and reduced toxic immunotherapy interventions. The extensive relationship between the immune system and cancer is opening up a new exploration hallmark for nanomedicine. Here, all the commonalities and synergies between these two fields are reviewed and described, as well as recent methods that show the advancement of biomarkers developed by banks in nanomedicine and tumor immunotherapy. In this regard, it has been shown that a variety of different nanomedicine formulations and macroscopic materials can stimulate immunity against cancer and the efficacy of immunomodulatory drugs. Keywords: Nanoparticles, Nanodiagnostics, Macroscale materials, Antigen Presenting cells
Publication date: 01/08/2022

https://ijbpas.com/pdf/2022/August/MS_IJBPAS_2022_6332.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.8.6332