ABSTRACT

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), is the virus that cause COVID-19 (coronavirus disease 2019), has become a major threat to the human society globally and has spread quickly became a pandemic. Several studies had been conducted about the inflammatory markers of covid-19. But strong evidence about the primary inflammation is yet to be understood. This study is aimed to compare the inflammatory markers with glycemic control among covid-19 patients. The cross sectional study was conducted with 130 participants in the age group 25-70 years. The participants were divided into 2 groups out of which, 62 COVID-19 positive individuals with HbA1C values less than 6.5 (< 6.5) were included in the group I and 68 COVID-19 positive patients with HbA1C ? 6.5 were included in the group II. The mean values of Ferritin, CRP, ESR, urea and uric acid were found to be elevated in the COVID-19 patients with HbA1c ? 6.5 (group II) when compared to the group I with HbA1c values < 6.5, but creatinine did not vary significantly among both groups. It is seen that the inflammatory marks like ferritin, CRP and ESR were found to be increased than normal in group I patients who are non-diabetic. This shows that the inflammatory marks may rise in COVID-19 patients. The renal function test which includes urea, creatinine and uric acid were under normal range in non-diabetics, but in diabetic individuals the levels were increased. Diabetic patients with higher HbA1C levels are more prone to develop severe COVID-19, as a result of significant relationship of HbA1C with inflammatory markers like ferritin, CRP and ESR. Hence, additional care must be taken to treat COVID-19 positive diabetic patients with increased HbA1C values who are at greater risk to develop severe conditions. Keywords: covid-19, HbA1c, Inflammatory markers, Diabetes mellitus
Publication date: 01/08/2022

https://ijbpas.com/pdf/2022/August/MS_IJBPAS_2022_6269.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.8.6269