ABSTRACT

Dendrimers are nanosized, symmetrical molecules having a small atom which is surrounded by many symmetric branches known as dendrons. Dendrimers structure possesses the greatest impact on drug release. They grow outwards from core-shell that further reacts with monomers. These are having high compatibility with the biological systems. The presence of hyper branching, the well-defined spherical structure are the unique characteristics. These dendrimers are having a wide range of applications including medical and biomedical areas. Nano formulations based on dendrimers enhances solubility of low soluble drugs, arrives to the target tissue, enhanced bioavailability and havecontrolled drug release. In this review, we mainly focussed on the types of nanosystems, synthesis, classification and applications of dendrimers in drug delivery. Dendrimer structures which are synthesized by two different methods that are divergent and convergent growth methods. Keywords: Dendrimers, Nano systems, Nano devices, Divergent and Convergent growth methods
Publication date: 01/07/2022

https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_6252.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.7.6252