ABSTRACT

Cholesterol is a key component of the central nervous system, as it is required for cell membrane stability and proper neurotransmission. Any substance shows its biological effect with in normal range; exceeding the normal range or below the range shows unwanted effects, similar with the levels of body cholesterol levels. Many of the hypothesis came out to show that low levels of serum cholesterol in blood leads to suicidal and violent behaviour in mood disorders. Some of the studies have proven that low cholesterol levels lead suicidal attempt of individuals, as low cholesterol leads to improper uptake of serotonin and low membrane viscosity of brain which leads to mood depressive disorders and which further provokes to suicidal behaviour. Relationship between serum cholesterol and suicidality, on the other hand, have been questioned in recent years, based on the findings of a few recent studies that showed no link. However, the discussion over the link between cholesterol and suicide is still ongoing, and longitudinal studies including a larger sample of patients are needed to better elucidate this crucial subject. The objective of our paper is to assess the relationship between levels of serum cholesterol and individuals attempting suicide. Keywords: Cholesterol, Suicide, Serotonin, Neurotransmission/Neuron communication, Mood disorders
Publication date: 01/07/2022

https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_6248.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.7.6248