LOCAL INJECTION OF PLATELET RICH PLASMA AND CORTICOSTEROIDS IN THE TREATMENT OF LATERAL EPICONDYLITIS OF HUMERUS: A RANDOMISED CONTROL TRIAL
Authors: Singh A , SATAPATHY D, SWAIN K*, MOHAN S, REDDY S, ZION N AND CHEKURI J

ABSTRACT
Back ground- Lateral epicondylitis is a commonly encountered entity caused by repetitive movements involving extensor tendons. Microscopic examination appears similar to angiofibroblastic hyperplasia. Corticosteroid injection has a short duration of action, yet local it is the gold standard for the management of lateral epicondylitis. It was hypothesised that PRP injection locally in long-standing tendinopathies can bring about increase in growth factor expression, cell proliferation, angiogenesis, increase the recruitment of cells that repair and increases tensile strength of tendons. Material and Method- Patients were included in the study after 2 months of conservative trail on anti-inflammatory, analgesics and a tennis elbow brace. Patients were randomized into two groups. Group I was given 2ml of freshly prepared platelet rich plasma with 2% of 1ml xylocaine and group II received 40mg methylprednisolone with 1ml 2% xylocaine. 101 and 112 patients respectively from group I and II were considered. Results- The mean VAS scores of patients in Group I and II before the procedure were 8.02 and 8.10 respectively, while at 2 weeks- 3.84 and 1.92 respectively and at 1 year- 2.58 and 5.60 respectively. The mean DASH scores of patientsig Group I and II before the procedure were 71.3 and 73.0 respectively, while at 2 weeks- 65.2 and 29.2 respectively and at 1 year33.1 and 68.6 respectively. There were similar trends seen with Mayo elbow performance scores and Grip strength. Conclusion- Although corticosteroid injections show better short term results but in the long term follow up their effect weans off while PRP continues to show its effect and gives long lasting relief to the patients. Keywords: Corticosteroids, Platelet Rich Plasma, Epicondylitis, Humerus
Publication date: 01/07/2022
    https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_6219.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.7.6219