ABSTRACT

Sodium-Glucose cotransporter-2 (SGLT2) inhibitors are an emerging therapeutic prospective for treating type-II diabetes and have revolutionized the concept of diabetes management. This review work compiles information from previously published techniques for analyzing Ertugliflozin either alone or infusing with other drugs. Several spectroscopic methods such as chromogenic technique and derivative technique have been used. This review has emphasized the different methods of HPLC and UPLC?MS/MS that have been used to analyze Ertugliflozin in several biological matrices. Relevant useful information on sample processing options, chromatographic/detection settings, and validation parameters of the selected Ertugliflozin procedures has been methodically gathered here in a simple manner. This brief review work would certainly lead an analyst to choose the appropriate method(s) for fresh analytical method development and validation of Ertugliflozin and similar drugs. Keywords: Chromogenic, UPLC-MS/MS, HPLC, Ertugliflozin
Publication date: 01/07/2022

https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_6213.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.7.6213