ABSTRACT

Medicines derived from medicinal plants and their derivatives are now preferred by physicians as remedies to mankind. India has rich biodiversity and near about 6000 medicinal plants are used in Indian system of medicines for the benefit of human being. Alternanthera ficoidea (L.) belongs to family Amranthacae, is used traditionally as medicine for the treatment of various diseases like diuretic, anti-pyretic, antiseptic, anti-inflammatory and anti-diarrheal agent. In the present investigation macroscopic, microscopic and powder microscopy studies and physicochemical analysis of crude drug of Alternanthera ficoidea were performed. Further, preliminary phytochemical analysis, quantitative phytochemical estimation and highperformance thin layer chromatography (HPTLC) profiles of its hydro-alcoholic extract was performed. The preliminary phytochemical studies of hydro-alcoholic extract and its fractionated extracts of Alternanthera ficoidea confirmed the presence of phytochemical like carbohydrate, steroid, tannins, flavonoids and phenolics. The quantitative estimation of total phenolics, total flavonoid and total tannin contents were estimated by spectroscopy method and determined as 6.11mg/g Gallic acid equivalent, 47.68 mg/g Quercetin equivalent, and 2.15 mg/g Tannic acid equivalent respectively. Further, HPTLC profiling of hydro-alcoholic extract of Alternanthera ficoidea with marker compounds confirmed the presence of bioactive constituents as tannic acid, lupeol and quercetin. These studies may be used as reference for the development of authentication monograph of this drug and recognition of Alternanthera ficoidea from the other species of Alternanthera. Keywords: Alternanthera ficoidea, Hydro-alcoholic, Ash value, Quercetin, and HPTLC
Publication date: 01/07/2022

https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_6196.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.7.6196