RANDOMIZED OPEN LEVEL PARALLEL CLINICAL TRIAL OF SHUNTHI CHURNA, RASNADI GUGGULU AND RUKSHA VALUKA SVEDA IN CASES OF RHEUMATOID ARTHRITIS VIS-À-VIS AMAVATA UNDER THE INFLUENCE OF DOMINANT SETS OF DEHA PRAKRITI
Authors: Singh AK , KATHAIT R, PANDEY AK* AND SINGH G

ABSTRACT
Background: Rheumatoid arthritis (RA) is a prevalent rheumatological condition in the society. It affects 1-3% of women in their life during middle age. It affects 1% of the population in India. The causes, diathesis and management of RA are still evolving in conventional system of medicine. Introduction of corticosteroids had brought big hope for the patients but because of its greater side effects. The overall role of steroids, Non steroidal anti-inflammatory drugs (NSAIDs) and Disease modifying anti-rheumatoid drugs (DMRDs) in the management of RA is very limited. Ayurvedic scholars in the medieval period have been vividly described the aetiopathogenesis and management of Amavata, which is comparable to RA of the conventional system of medicine. In the last few decades, researches have been conducted by research scholars but all of them did not show any major breakthrough. In this emerging scenario, the author has decided to launch a clinical study to evaluate the efficacy of Shunthi Churna, Rasnadi Guggulu and Ruksha (Valuka) Sveda in a series of patients of RA vis-à-vis Amavata under the influence of dominant sets of Deha Prakriti. Ayurveda strongly believes that based on Prakriti every individual has its genetic makeup and it varies from person to person. So, the response of drugs and therapeutic measures is also different from person to person either it is belonging to Ayurvedic or modern drugs. Methods: The present clinical study was launched to conduct an open parallel clinical trial in 60 patients (20 in each group) diagnosed (based on EULAR 2010 revised criteria) with Rheumatoid arthritis (Amavata), allocated randomly in the (ratio of 1:1:1) three parallel groups based on three dominant sets of Deha Prakriti viz. – Group A - Vata dominant, Group B - Pitta dominant and Group C - Kapha dominant, respectively. Each group was treated with a package of Ayurvedic drugs (Shunthi churna
Publication date: 01/07/2022
    https://ijbpas.com/pdf/2022/July/MS_IJBPAS_2022_5808.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.7.5808