ABSTRACT

Natural products have been an important resource for the maintenance of life since ages. Natural products are becoming increasingly important as alternative medicines. Side effects associated with allopathic drugs and synthetic compounds have prompted research into herbal and natural products. In India there has been interest in the potential of natural products obtained from plants and animals for development of drugs with wound healing properties as taught in a popular form of Indian medicine known as Ayurveda. Along with other dosage forms herbal drugs are also formulated in the form of ointment. The present work aims to formulate polyherbal ointment and evaluate whether combination of plant extracts produces any synergistic effect on wound healing. Two different formulations were made with Lantana camara, Curcuma longa, Tamarindus indica and Psidium guajava. Both formulations showed significant effect which was comparable with standard. Standard Soframycin 2% showed 91.13% protection. Among the two prepared formulations formulation 1 exhibited 93.03% protection which is significant to that of standard (p?0.05). This may be due to the synergistic effect of phytochemicals like alkaloids and saponins present in the plant extracts. Keywords: Lantana camara, Curcuma longa, Tamarindus indica, Psidium guajava, alkaloids and saponins
Publication date: 01/06/2022

https://ijbpas.com/pdf/2022/June/MS_IJBPAS_2022_6153.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.6.6153