Long-term UV exposure can cause major side effects, including photoaging, wrinkles, and the
development of skin cancers, including melanoma and non-melanoma cancer. The formation of
erythema and erosions is triggered by such UV exposure, which is regulated by mutation,
apoptosis, carcinogenesis, and immunosuppression. The purpose of this review was to discuss
flavonoids and their role in photoprotection. In the skin epidermis and dermis, flavonoids
(catechin, genistein, naringenin, and Kaempferol) may prevented UV-B induced erythema and
reduced the development of cyclo-butane pyrimidine dimers in the DNA. When administered
topically, flavonoids protect DNA while also preventing other UV-light-induced effects such as
sunburn, immunosuppression, and skin photoaging. It also lowers the risk of skin cancer and
improves the condition of the skin. We discussed the health-related issues of chemical
photoprotection agents, including their side effects and stability in hormone dysfunction, as well
as some major environmental issues. However, in the Present Scenario; The aim of this review to
protect our skin from UV radiation as well as sunscreen also using sunscreen have a number of drawbacks, including the development of photoallergy dermatitis, pollution, and vitamin D
insufficiency. As a result, Customers should use the right items to increase and protect our skin
towards radiation and avoid the negative effects of sunscreen.
Keywords: Photoprotection, Flavonoids, Immunosuppression, SPF factor, Photoaging, UV
radiation, Nanotechnology
Publication date: 01/05/2022
https://ijbpas.com/pdf/2022/May/MS_IJBPAS_2022_6106.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.5.6106
