ABSTRACT

Artemesia rutifolia is extensively grown in Pakistan. In classical and herbal medicine this plant is used extensively to treat various disorders. Present study was designed to perform qualitative and quantitative phytochemical analysis, antioxidant potential, and antimicrobial potential of Artemisia rutifolia against gram-positive and negative bacteria. The plant was collected, identified, and processed for Extract preparation in Methanol, Ethanol, Water, Acetone, and Hexane (MEWAH) solvents. Phytochemical Analyses and quantification were done through GCMS. Antibacterial and antioxidant potential of plant extract were identified. Artemisia rutifolia reveals a large percentage of alkaloids and Phenols. Water extract exhibited excellent percentage of Flavonoids. However, methanol extracts are considerably rich in Phenols. Total 89 phytochemicals were detected in MEWAH extracts except for water that had none. Medicinally important antitumorigenic, antiinflammatory and anti-ischemic molecules like thujone, Cis-Verbenol, Phorbol, Gitoxigenin, Stigmasterol, and Eupatorin were identified in Artemisia rutifolia extracts. Moderate to excellent Antibacterial activity for L. Lactis B. Subtilis, C. freundi and L. monocytogenes, E. coli, and K. oxytoca strains was recorded. Acetone extract have highest antioxidant radical scavenging activity. Artemisia rutifolia is extremely rich source of phytochemicals and antioxidants functional against bacterial infections, showing radical scavenging activities and anti-tumorigenesis potential. Keywords: Artemisia rutifolia, GC/GC-MS; Plant Biotechnology, Herbal Medicine
Publication date: 01/05/2022

https://ijbpas.com/pdf/2022/May/MS_IJBPAS_2022_6089.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.5.6089