ABSTRACT

The present review focuses on estimation of Ribavirin its combination of drugs by different analytical techniques. Ribavirin is very effectively used as an antiviral drug. It isused with an interferon medication such as peginterferon alfa-2a [Pegasys] or peginterferon alpha-2b [PEG-Intron]) to treat hepatitis C. In this review various analytical methods such as Highperformance liquid chromatography (HPLC), High performance thin layer chromatography (HPTLC), Liquid Chromatography Mass Spectroscopy (LC-MS) for the estimation of Ribavirin in bulk and pharmaceutical dosage forms in various researchers’ publications. This review enlightens the various solvents and conditions suitable for the estimation of Ribavirin and its combination of drugs. The techniques illustrated here may find application in the qualitative and quantitative estimation of Ribavirin and in analysing other related properties. Keywords: Ribavirin, Antiviral agent, HPLC, HPTLC, Hyphenated Techniques
Publication date: 01/05/2022

https://ijbpas.com/pdf/2022/May/MS_IJBPAS_2022_6077.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.5.6077