ABSTRACT

Marine microalgae, Dunaliella salina (green algae) was selected for the present secondary metabolite investigation. In the present work, the production of bioactive compounds by Dunaliella salina and their antibacterial activities were investigated against different bacterial pathogens. The antibacterial effect of the methanol extract of Dunaliella salina exhibited maximum zone of inhibition (16.18±0.23 mm) against S. epidermidis. The methanol extracts were characterized by FTIR and GC–MS. Dimethyl sulfoxide and 2- Pyridinecarboxylic acid from polar compounds were determined with the highest amount in methanol extracts of the microalga were detected. However, pigments such as chlorophyll a, b and total carotenoid with antibacterial activity were identified, Dimethyl sulfoxide and 2- Pyridinecarboxylic acid responsible for the antibacterial activity were analyzed. The GC-MS analysis revealed that the presence of unique chemical compounds like Dimethyl sulfoxide (M.W. 78), 2-Pyridinecarboxylic acid (M.W. 137), Dimethyl Sulfone (M.W. 94), and Benzenepropanoic acid, alpha., 4-dihydroxy-, methyl ester (M.W. 196) respectively from the crude extract of Dunaliella salina. Keywords: Dunaliella salina, methanol solvent, antibacterial activity, bioactive compounds, FTIR and GC–MS
Publication date: 01/05/2022

https://ijbpas.com/pdf/2022/May/MS_IJBPAS_2022_5712.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.5.5712