ABSTRACT

Fabrication of biologically synthesized nanoparticles played a vital role in the catalytic method of green synthesis. In the current study, a simple and environmentally convenient method was used for the synthesis of silver nanoparticles using the leaf extract of Piper betle (L) var. sirugamani 1 (SGM1). The biosynthesized silver nanoparticles were characterized by using scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), Energy dispersive X-ray spectroscopy (EDAX) technique, Ultra-violet spectroscopy (U.V), and Fourier transform infrared spectroscopy (FTIR). The FTIR confirms the modes of spherical phase due to the stretching and bending vibrations with the spectral peaks of 3450.80, 1634.74, 1519.97, and 682.83cm-1. The surface plasma absorption band occurred at a maximum average of 200-800 nm indicating the presence of spherical Ag nano particles through UV-Vis spectroscopy. The elemental analysis of the bio synthesized silver nanoparticles was confirmed by EDAX spectroscopy. Scanning Electron Microscope technique was employed to visualize the size and shape of silver nano particles. The average sizes were found to be 18.24nm, 20.73nm, 25.81nm, 32.17nm in Sirugamani-1. The antidiabetic activity of silver nanoparticles was confirmed by ?-Amylase Inhibition Assay, ?-Glucosidase Inhibition Assay, and anti-inflammatory activity was assessed using Albumin Denaturation Technique and HRBC stabilization method. Keywords: Biosynthesized Silver nanoparticles, Sirugamani-1 piper betel cultivar, Antidiabetic activity, and Anti-inflammatory activity.
Publication date: 01/04/2022

https://ijbpas.com/pdf/2022/April/MS_IJBPAS_2022_6041.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.4.6041