COMPARATIVE IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF GOMUTRA SADHITA TRIPHALA KWATHA AND GOMUTRA SADHITA TRIPHALA ARKA Authors: Pathania S , JHA LL, MISHRA AK AND RAGHUVEER H
ABSTRACT
Inflammation in Ayurveda can be correlated with Shotha. There are formulations in Ayurveda which
are indicated in Shotha. Some of the formulations remained untouched. Here one formulation
Gomutra Sadhita Triphala kwatha in Ayurvedic texts is explained in the Shotha conditions. But due
to some lacunas in Kwatha kalpana the dosage form was changed into Arka. Then both kalpanas were
taken for the in-vitro anti-inflammatory study. Protein denaturation is documented cause of
inflammation. So change in protein denaturation suggests changes in inflammation. If protein
denaturation is inhibited it is told that inflammation can also be inhibited. Protein denaturation
inhibition was used to assess anti-inflammatory efficacy in vitro. Bovine serum albumin was used in
the protein denaturation inhibition study at different concentrations. After the study it was found that
both Kwatha and Arka have anti-inflammatory properties as percentage of inhibition was found to be
good at different concentrations. Gomutra Sadhita Triphala kwatha was having high percentage of
inhibition than the Gomutra Sadhita Triphala arka.
Keywoerds: Kwatha, Arka, Anti-Inflammatory, In-Vitro Study Publication date: 05/03/2022 https://ijbpas.com/pdf/2022/March/MS_IJBPAS_2022_MARCH_SPCL_1081.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2022/11.3.1081