COMPARATIVE IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF GOMUTRA SADHITA TRIPHALA KWATHA AND GOMUTRA SADHITA TRIPHALA ARKA
Authors: Pathania S , JHA LL, MISHRA AK AND RAGHUVEER H

ABSTRACT
Inflammation in Ayurveda can be correlated with Shotha. There are formulations in Ayurveda which are indicated in Shotha. Some of the formulations remained untouched. Here one formulation Gomutra Sadhita Triphala kwatha in Ayurvedic texts is explained in the Shotha conditions. But due to some lacunas in Kwatha kalpana the dosage form was changed into Arka. Then both kalpanas were taken for the in-vitro anti-inflammatory study. Protein denaturation is documented cause of inflammation. So change in protein denaturation suggests changes in inflammation. If protein denaturation is inhibited it is told that inflammation can also be inhibited. Protein denaturation inhibition was used to assess anti-inflammatory efficacy in vitro. Bovine serum albumin was used in the protein denaturation inhibition study at different concentrations. After the study it was found that both Kwatha and Arka have anti-inflammatory properties as percentage of inhibition was found to be good at different concentrations. Gomutra Sadhita Triphala kwatha was having high percentage of inhibition than the Gomutra Sadhita Triphala arka. Keywoerds: Kwatha, Arka, Anti-Inflammatory, In-Vitro Study
Publication date: 05/03/2022
    https://ijbpas.com/pdf/2022/March/MS_IJBPAS_2022_MARCH_SPCL_1081.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.3.1081