CYTOTOXIC EFFECT OF TAMRA ON HEPATIC CELL CANCER CELL LINES - A CRITICAL REVIEW Authors: Anitha H , PANDYA MR AND TOSHIKHANE H
ABSTRACT
The Ayurvedic system of medicine has great antiquity, dating back to about 5000
years B.C. In the medieval period with the advent of Rasashastra use of different
Metals, Minerals in therapeutics was intiated. Tamra (Copper) is one such metal
included under shudda loha varga and is recommended in the management of various
disorders such as Shwasa, Yakrut Vikara, sthoulya Arbuda etc, Different compounds
of Copper I,e Tamra Bhasma, Tamra Sindhura, Tamra garbha Pottali are potential
therapeutic agents, As Tamra and its formulations are indicated in Yakrut vikara, they
can prove effective in Hepatocellular carcinoma. The Anti-Cancer action or cytotoxic
action of Tamra can be screened on Human Cancer cell line studies (Hep G2, Hep B3)
using MTT Assay method. This is a reliable and easily feasible method to
scientifically validate and aid in the development of new anticancer agents.
Keywords; Cell Line Studies, Cancer, Tamra Publication date: 05/03/2022 https://ijbpas.com/pdf/2022/March/MS_IJBPAS_2022_MARCH_SPCL_1070.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2022/11.3.1070