ABSTRACT

Huntington's disease (HD) is a neurodegenerative disease that affects people of all ages. Chorea and dystonia, as well as mental illness, memory loss, and weight loss, are all symptoms of accelerating motor disorder. Spiny striatum and cortex neurons in the medium size range in HD, they are predominantly carried out. Different assumptions, including molecular genetics, oxidative stress, excitotoxicity, metabolic stress and mitochondrial dysfunction are the reason for neuron dysfunction and destruction of cells. While no cure is possible to entirely avoid the progression of the disease, there are medications available to prevent the disease from developing. Assist in managing the Chorea. The present analysis focuses on brief disease pathophysiology, plants and phytochemicals those are explored in the management of HD. Keywords: Huntington's disease (HD), phytochemicals, pathophysiology, Chorea and dystonia
Publication date: 01/03/2022

https://ijbpas.com/pdf/2022/March/MS_IJBPAS_2022_5926.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.3.5926