Family Leguminosae's Sesbania grandiflora is rich in sterols, saponins, and tannins, which give it a wide
range of medicinal benefits. Roots, bark, leaves, flowers, and fruits are only some of the plant
components that have been studied for their unique pharmacological effects. Tannins, flavonoids,
coumarins, steroids, triterpenes, and isovestitol, and medicarpin are all found in high concentrations in the
plant, as is satan betulinic acid. Sesbania grandiflora can be used alone or with other herbs to treat a wide
range of diseases. Dementia is a loss of cognitive ability that impairs daily activities and daily routines.
One to four percent of the world's population over 65 has some kind of Dementia, a set of degenerative
disorders involving brain cells degenerating. A variety of different etiologies causes Alzheimer's disease.
Heart illness and neurodegenerative conditions (such as hypertension, hypercholesteremia, and diabetes)
put patients at greater risk of Dementia. Other risk factors for this neurodegenerative disease include
excessive alcohol usage and smoking. Alzheimer's disease, vascular Dementia, frontotemporal Dementia,
semantic Dementia, and Dementia with Lewy bodies are the most frequent types of Dementia. The
elderly are more likely to develop Alzheimer's disease or Dementia with Lewy bodies. Long-term
cardiovascular disease (CVS) can trigger Vascular Dementia (VaD), the second most frequent form of
Dementia after Alzheimer's disease (AD). Dementia with semantic memory loss is referred to as semantic Dementia (knowledge of objects, people, concepts, and words). Aggregation of synuclein hinders
neuronal growth in Lewy body dementia (LBD) and is critical in the disease's pathophysiology. For this
review, we looked at the effectiveness of Sesbania grandiflora in treating Dementia. Dementia-treating
various medicinal plants are described in this article.
Keywords: Dementia, Alzheimer's disease, Sesbania grandiflora, Antioxidant, Phytochemicals
Publication date: 01/12/2021
https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_2038.pdf
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https://doi.org/10.31032/IJBPAS/2021/10.12.2038
