ABSTRACT

Cancer is a common cause of death nationwide. Breast cancer is projected to be among the most common cancer and is the most frequent malignant neoplasm in women. Therefore, it is necessary to find novel therapeutic agents against cancer, which are biocompatible and cost effective. The development of nanotechnology has been a boon to mankind as its significance paved the way for several applications. In the medical aspects, applications of nanoparticles increased tremendously only when the biological approach for nanoparticle synthesis came into focus. Therefore, this study was designed to synthesize ZnO NPs using Ipomoea carnea flowers and to evaluate potential in MCF-7 (Human Breast Adenocarcinoma) and L929 (Fibroblast) normal cells. Results of the present study concluded that the most potent undoped ZnO nanoparticles exhibit anticancer activity by inducing cell toxicity and apoptosis (morphology change) in MCF-7 cells and safer for L929 cells. Keywords: Ipomoea carnea flowers, MCF-7 cells, L929 cells, Cytotoxicity
Publication date: 25/01/2022

https://ijbpas.com/pdf/2022/January/MS_IJBPAS_2022_JAN_SPCL_2_20681.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2022/11.1.2068