ABSTRACT

Objective: To analyze pharmacognostic, phytochemical and evaluate in vitro antioxidant properties and to assess the alkaloids present in the Solanum giganteum leaf. Methods: It includes a study of leaf macroscopic features, microscopic features and physicochemical parameters evaluated using standard procedures as per WHO guidelines. In vitro antioxidant DPPH, H2O2 and NO radical scavenging estimated standard methods. Alkaloid solasodine is isolated from Solanum giganteum leaf and performed various characterization tests. Result: In microscopy of Solanum giganteum leaf are having Upper epidermis, trichomes, vascular bundle, collenchyma, the lower epidermis. In powered characteristics, Lignified trichomes, Brownish matter, Non-lignified fibre, Starch grain and Calcium oxalate crystal is observed. A low amount of total ash acid insoluble ash and water-soluble ash indicate that the inorganic matter and non-physiological matter such as silica is less in Solanum giganteum Jacq leaves. The estimation of total phenolic content in the examined extracts showed SG-Chloro extracts contain high phenolic content than SG-Alcohol and SG-Pet ether. The results of antioxidant evaluation based on the three models (DPPH, H2O2 & NO) used in this study revealed that Chloroform and Alcohol extract of Solanum giganteum leaf possess interesting antioxidant activity. Alkaloid solasodine is isolated from Solanum giganteum and performed variouscharacterization tests like melting point, optical rotation, solubility, TLC, IR characterization test results of standard solasodine and isolated solasodine same was found. Conclusion: The pharmacognostic, phytochemical analysis can contribute to the development of the quality control norms for this species. This plant may possess considerable antioxidant activities. Keywords: - Solanum giganteum, Pharmacognostic, antioxidant activities, Solasodine
Publication date: 25/01/2022

https://ijbpas.com/pdf/2022/January/MS_IJBPAS_2022_JAN_SPCL_2_2066.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.1.2066