Background: Thyroid disorders are one of the most prevalent endocrine diseases in the
world. Metabolic syndrome is associated mainly with the thyroid dysfunction which impact
on glucose, lipid metabolism and cardiac dysfunction.
AIM& OBJECTIVE: Tostudythyroiddysfunction inmetabolic syndrome.The main objective
of this study was to study the pattern of thyroid dysfunction in casesof metabolic syndrome
and to evaluate the association of thyroid dysfunction with thecomponents of metabolic
syndrome
METHODOLOGY: It was a Crosssectional Observational study. The Study was conducted
at outpatient department and wards of Dr DY Patilmedicalcollegeand hospital, DY Patil
Vidyapeeth, Pimpri, Pune. Outpatient department wards of tertiary care hospital. Registration
ofpatients was from August 2019. They were registered when admitted under Medicine
department.
RESULTS: In the present study, mean age in years was 49.27 + 8.99 years. Majority 50%
were in the age group of 46 to 55 years. Majority were females with 58% and 42% weremales. Number of Criteria positive for metabolic syndrome among study subjects, majority
48% had 3 parameters, 30% had 4 parameters and 22% had 5 parameters positive. On general
examination, mean age was 49.27+8.99, height was 156.5+0.04, weight was 79.4+12.2, waist
circumference was 102.44+10.68, systolic blood pressure was 129.2+8.36, diastolic blood
pressure was 88.88+10.46, fasting bloodsugar 160.7+54.96, total cholesterol was
131.84+21.2,HDL was52+20.65,triglyceridewas146.53+42.25.In present study Thyroid
dysfunction was seen among 22% of metabolic syndrome patients. Majority 78% had
euthyroid status, 15% had subclinical hypothyroid, 4% had hypothyroid, 2% had subclinical
hyperthyroid, and 1% had hyperthyroidism. In present study majority 78% had euthyroid
status, 15% had subclinical hypothyroid, 4% were hypothyroid, 2% had subclinical
hyperthyroid, and 1% hadhyperthyroidism. No statistical significance was seen between
gender and thyroidstatus (P=0.73). Nostatistical significance was seen between ageandthyroid
status(P=0.98). Strong association of thyroid dysfunction with the components of metabolic
syndrome was seen (p<0.0001).
CONCLUSION: The study conclude that thyroid functions should be taken into account
while treating a patient with metabolic syndrome which will help in early diagnosis of thyroid
dysfunction and thus decrease the incidence of a therosclerotic cardiovascular disease risk.
Keywords: Thyroid, Metabolic syndrome, HDL, euthyroid, Cardiovascular disease
Publication date: 15/02/2022
https://ijbpas.com/pdf/2022/February/MS_IJBPAS_2022_FEB_SPCL_1039.pdf
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https://doi.org/10.31032/IJBPAS/2022/11.2.1039
