ABSTRACT

This study was aimed to determine the vitamin D status in pregnant women attending a tertiary care hospital and its association with pregnancy outcomes and to determine the correlation between maternal and cord blood vitamin D levels. Three hundred & sixty consecutive primigravidae with singleton pregnancy admitted to the labour ward of a tertiary care centre were recruited for the study. Women with type 1 DM, malabsorption, hepatic/renal/adrenal diseases, overt thyroid/parathyroid diseases, metabolic bone diseases and women not willing to participate were excluded from the study. Maternal and cord blood samples were taken and analyzed for 25 (OH) D level. Maternal outcomes and cord blood levels were studied. High prevalence of hypovitaminosis D was found among pregnant women. 57.8% women had insufficiency, 24.4% had deficiency and only 17.8% women had sufficient levels of vitamin D. Abnormal pregnancy outcome was noted in the form of antenatal complications like preeclampsia, gestational hypertension, eclampsia, GDM and PROM. Ladies with strange pregnancy results had genuinely huge nutrient D inadequacy and deficiency when contrasted with ladies with typical result (p=0.001). Mean vitamin D levels among women with preeclampsia, gestational hypertension, eclampsia, GDM and PROM were 14.3 ng/ml, 17.1 ng/ml, 16.4 ng/ml, 22.7 ng/ml, 20.6 ng/ml, 24.3 ng/ml respectively which were significantly low as compared to 34.2 ng/ml in women with normal outcome (p=0.001). Cord blood vitamin D levels strongly correlated with maternal vitamin D levels (p=0.001).This examination showed an exceptionally high predominance of hypovitaminosis D among pregnant ladies and magnificent connection among's maternal and fetal nutrient D levels. Toxemia was the most well-known antenatal confusion in this examination. Keywords: Gestational hypertension; Hypovitaminosis D; Preeclampsia; Pregnancy outcomes
Publication date: 15/02/2022

https://ijbpas.com/pdf/2022/February/MS_IJBPAS_2022_FEB_SPCL_1038.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.2.1038