A COMPARATIVE STUDY OF ACCURACY (NEUTROPHIL TO LYMPHOCYTE RATIO) AND MCTSI (MODIFIED CT SEVERITY INDEX) SCORING SYSTEM IN PREDICTING THE SEVERITY OF ACUTE PANCREATITIS
Authors: Shet DH , KSHIRSAGAR AY AND KATKAR A

ABSTRACT
BackgroundAcute pancreatitis is considered as an acute GI condition which is treated as an emergency. It is a lifethreatening disease causing significant morbidity and if it progresses to severe form then the prognosis is poor. Biochemical investigations like serum amylase and lipase level and USG are mainly used for the diagnosis of acute pancreatitis. Gold standard modality for diagnosing acute pancreatitis is CECT. Scoring systems consist of both biochemical and radiological investigations. However, these modalities needs several laboratory investigations which are expensive. MethodologyRetrospectively data was collected of patients who were diagnosed as acute pancreatitis. Biochemical markers along with routine blood investigations and radiological investigations such as USG and CT scan were done. Neutrophil to Lymphocyte Ratio and MCTSI, and its accuracy in predicting the severity of acute pancreatitis was seen with the help of revised Atlanta classification.Patients having comorbidities (e.g., diabetes and hypertension) - 25 Comparison of NLR with revised Atlanta classification showed that it is a good predictor of severity in severe, fair predictor in moderate and excellent predictor in mild cases. ConclusionFrom this study we could conclude that compared to MCTSI, Neutrophil to Lymphocyte is better in assessing the severity of acute pancreatitis along with the revised Atlanta classification. On the basis of various results observed in our study, it can be said that NLR is a better parameter as it is inexpensive, easily available and less time consuming. This in turn helps in decreasing mortality and morbidity by evaluating the disease early and on time.

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https://doi.org/10.31032/IJBPAS/2022/11.2.1010