ABSTRACT

Introduction: Aging occurs in all living organisms and it is an inevitable process. Aging is caused due to both intrinsic and extrinsic factors. Intrinsic aging is an inevitable physiological process. Extrinsic aging occurs in addition to intrinsic aging as a result of sun and environmental damage. Activation of hyaluronidase, collagenase and elastase, leads to skin aging. By using the medicinal crop Linum usitatissimum were investigated to assess their skin aging properties. Methods: The activity of anti- elastase, anti- collagenase and anti-hyaluronidase in ethanol extract from the seed of Linum usitatissimum was determined by using spectrophotometric methods. The bio-active compounds of Lainum usitatissimum was analyzed using GC-MS method. Result: The anti-elastase assay in ethanol extract of Linum usitatissimum shows 70% inhibition, for anti- collagenase assay shows 73% inhibition and for anti-hyaluronidase assay shows 61% inhibition. The ethanol extract of Linum usitatissimum contained the highest anticollagenase activity. Conclusion: The enzymes which are responsible for aging is inhibited by ethanol extract of Linum usitatissimum, suggests that it can help to restore skin elasticity and slows down the process of aging. Keywords: Anti-ageing Activity, Linum usitatissimum, Spectrophotometric method, GCMS Techniques
Publication date: 01/02/2022

https://ijbpas.com/pdf/2022/February/MS_IJBPAS_2022_5894.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.2.5894