ABSTRACT

Background: Congenital anomalies are important causes of still births, infant mortality and are contributors to childhood morbidity. Congenital malformation represents defects in morphogenesis during early foetal life. The estimated 303000 newborn die in 4 weeks of birth every year, throughout the world due to congenital anomalies. Data reveals that 11.1% of pediatric hospital admissions are for children with genetic disorders, 18.5% are children with other congenital malformations. As per the Data to March of Dimes (MOD) global report on birth defects 7.9 million births (6% of total births) occur annually worldwide with serious birth defects and 94% of these births occur in the middle and low income countries. According to joint WHO and MOD meeting report, birth defects account for 7% of all neonatal mortality and 3.3 million under five deaths. The prevalence of birth defects in India is 6-7% which translates to around 1.7 million birth defects annually. The common birth defects include congenital heart disease (8-10 per 1000 live births), congenital deafness (5.6-10 per 1000 live births), and neural tube defects (4-11.4 per 1000 live births). Some birth defects are clinically apparent at birth; others may only be diagnosed during later stages of life. Material and Materials: The following are the databases followed- PubMed, Science direct, Google Scholar, DHARA, and AYUSH Portal. A search was undertaken in the Pub-Med database, using keywords Ayurgenomics, congenital anomalies, Prakriti, phenotype as the mesh term. There were 2692 articles available. Nine articles available in Google scholar and four articles from DHARA were also shortlisted. After using various filters only five articles were found most relevant and were considered as the reference for the present review. Textual references considered are the classics Charaka Samhita, Susruta Samhita, Ashtanga Samgraha and Ashtanga Hridaya with special reference to Shareera Sthana Conclusion: There are Multiple Causes of congenital anomalies which are associated with lack of supervision, care and prevention through diet, mode of action and mental health Multiple antenatal factors those influencing physical and psychological development of child are well described in Ayurveda. Keywords: Congenital Anomalies, Viruddha Ahara, Ayurveda Prevention and Mitigation
Publication date: 25/01/2022

https://ijbpas.com/pdf/2022/January/MS_IJBPAS_2022_JAN_SPCL_2_2036.pdf

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https://doi.org/10.31032/IJBPAS/2022/11.1.2036