ABSTRACT

Introduction: Dyslipidemia is abnormal levels of low density lipoproteins LDL, VLDL and low levels of HDL. The common causes include genetic factors, poor diet and sedentary life style, excessive alcohol intake, obesity, diabetes, kidney disease, hypothyroidism and certain drugs1 . According to Ayurveda, it can be categorized under Medovahasroto dushti2 or Medodhatuagnimandya. Several formulations were utilized for treatment of dyslipidemia. This study is unique by reporting the efficacy of Yavalauhachurna in the treatment of dyslipidemia. Clinical findings: A female patient aged 52 years complained of generalized weakness (daurbalya) associated with excess thirst (ati-pipasa), excess sleep(nidra-aadhikya) and excessive perspiration (atisweda). Laboratory investigations mentioned Hyperlipidemia with increased levels of total serum cholesterol (475.7 mg/dl), serum triglycerides (280.2 mg/dl), serum Low Density Lipoprotein (205.7 mg/dl), serum very Low Density Lipoprotein (89.1 mg/dl) and low High Density Lipoprotein (34.5 mg/dl). Diagnosis: The disease was diagnosed as Medoroga in Ayurveda and Dyslipidemia as per contemporary science. Therapeutic intervention and outcomes: The intervention of trial drug – Yavalauhachurna lowered the various components of deranged lipid profile. The GCMS (Gas chromatography and mass spectrometry) study was conducted to understand the probable mode of action and validate the findings.Conclusion:The results will add on to the scientific literature by providing evidence based practice for tackling the condition of deranged lipids. This study paves the way for further larger clinical trials. Key words: Dyslipidemia, Yavalauhachurna, Ayurveda, Medoroga, Randomised Controlled Clinical Trial, Case report
Publication date: 25/01/2022

https://ijbpas.com/pdf/2022/January/MS_IJBPAS_2022_JAN_SPCL_2_2028.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2022/11.1.2028